Since being given a significance by Mencius pertaining to the establishment of the theory that human nature is good, ren, yi, li, and zhi, which are commonly translated as benevolence, dutifulness, ritual, and wisdom, respectively, have traditionally been taken as main concepts by Confucians, including Tang Junyi undoubtedly, whose interests are themes including human nature, self-cultivation, as well as the essence of Dao. Focusing on Tang’s writings connecting to the four concepts mentioned above, it will be argued that Tang not only provided a reasonable interpretation of Mencius’s view on the goodness of human nature, but constituted a new theory where new meanings of, and new relations among, ren, yi, li, and zhi are created. Besides, it will too be claimed that, from a methodological point of view, the slogan of “ren-yi-li-zhi,” as originally a mere research material, has creatively been refined as a conceptual framework.