以ANOVA分析濃縮葡萄汁粉抗炎功效之研究

A study on the anti-inflammatory effects of concentrated grape juice powder analyzed by ANOVA

葡萄（Vitis vinifera L.）是人類飲食中已知最古老的有益營養成分之一，其高多酚含量已被證明可以增強人類健康。本研究目的為驗證濃縮葡萄汁粉體外抗炎發活性之功效。研究方法以ANOVA進行分析，以抑制脂多醣（LPS）誘導的抗發炎作用，分析巨噬細胞中，一氧化氮（NO）、介白素6（IL-6）、腫瘤壞死因子（TNF-α）的發炎因子生成量變化，使用不同濃度分析。研究結果顯示，濃縮葡萄汁粉可抑制NO生成量，表現出顯著抑制發炎功效；但對抑制IL-6與TNF-α生成則無顯著抗發炎作用。本研究結論揭示，濃縮葡萄汁粉表現出具抗發炎作用，可提供作為人類營養保健參考。

Grapes (Vitis vinifera L.) are one of the oldest known beneficial nutrients in the human diet. Its high polyphenol content has been shown in studies to enhance human health. The purpose of this study was to verify the anti-inflammatory activity of concentrated grape juice powder in vitro. The research method was analyzed by ANOVA to inhibit the anti-inflammatory effect induced by lipopolysaccharide (LPS) and analyze the changes in the production of inflammatory factors such as nitric oxide (NO), interleukin 6 (IL-6), and tumor necrosis factor (TNF-α) in macrophages using different concentrations. The results of the study showed that concentrated grape juice powder can inhibit the production of NO and show significant anti-inflammatory effects; however, it has no significant anti-inflammatory effect on inhibiting the production of IL-6 and TNF-α. The conclusion of this study revealed that concentrated grape juice powder exhibits anti-inflammatory effects and can provide a reference for human nutrition and health care.