To cope with energy shortage problem, Taiwan Government continues to promote smart green buildings. Therefore, it is important to study how to maximize the operational performance of energy-saving for those smart green buildings, particularly for those receiving the highest-level smart green building badge certificate. The purpose of this paper is to present a managerial energy saving model for smart green buildings. This study used the case of Central Taiwan Industrial Innovation Campus to exemplify the managerial model. During operation, the Measure, Manage, Reduce system was used to integrate the micro-smart grid system and building information model with space management information. Thus, detailed energy consumption data for various types of space and facility system were aggregated. Meanwhile, statistical analyses were performed in terms of time sequence and influencing power consumption factors. Moreover, linear regression and support vector machine technology were used to specify the energy consumption baseline for each space and facility system. Then, a set of energy-saving management models for operation control was constructed to enhance the effective energy saving for smart green buildings. In addition to revealing power consumption information in detail for various types of space and facility of the R & D building, the modeling framework can be used by architects, property owners, and property managers as a useable reference for energy-saving management.