This study aimed to explore the ambiguous loss experiences and the adjustment meanings of the missing companion animals. This study adopted the inductive thematic analysis, conducting an in-depth interviewing, semi-structured questions to collect three research participants’ rich narratives. The results first presented the process of encounters, interactions, disappearances and separations between our participants and their companion animals. The ambiguous loss experiences of the missing companion animals were as follows: (1) Can’t bear to think that it is dead, but hope it can escape danger and find safety; (2) Feeling helpless and getting tired gradually, expectations were fading because of without supporting; (3) To leave or disposed of what it left behind? Views of self and others, each justified. The adjustment meanings of the ambiguous loss experiences included: (1) Don’t be obsessed with "why", accepting the facts and sending blessings; (2) Create their own rituals to say goodbye, and endless thinking will make the companion animals still be with you. Based on the above research results, this study tried to divide the ambiguous loss of companion animals into five stages: mobilization period, dynamic negotiation period, prayer period, return to normal life period, and continuous bond period. The suggestions put forward by this study are: (1) Give time to the clients who want to find their companion animals in the early stage of missing, do not obliterate their hopes so quickly, and accompany them to do something within their capabilities; (2) Allow the clients to do imagine good life of the missing companion animals, and encourage the client to send blessings to the companion animals; (3) Assist the clients to accept loss and ambiguity, and find a new direction of their life; (4) Assist the clients to construct the meaning of losing the companion animals, and develop appropriate ceremony to honor companion animals.