Japan entered the stage of a super-aged society in 2007. In such a society, multiple phenomena have been progressing simultaneously, including the extension of life expectancy, the increase in the elderly population, and the rising costs of national medical care and long-term care. This study, based on the concept of "health transition," constructs an econometric model of long-term care demand comprising six equations, with proxy variables such as chronic diseases, senescence-related diseases, healthy life expectancy, average life expectancy, aging, and long-term care expenditures. Using data from 2000 to 2020, estimations were conducted through multiple linear regression (OLS) and the generalized method of moments (GMM). The results showed that the adjusted coefficient of determination reached 0.9, and the main explanatory variables were statistically significant (P < 0.01). In particular, average life expectancy and senescence-related diseases were identified as direct determinants of changes in longterm care demand. These findings not only contribute to the formulation of long-term care policies in Japan but also provide important implications for the projection of future long-term care demand and the design of relevant systems in Taiwan, which is also transitioning into a super-aged society.