Background: Surgical smoke poses a major health risk to medical personnel and patients in the operating room. Although smoke evacuation systems provide an effective countermeasure, they have not yet been widely adopted in clinical practice. This literature review aims to further explore the barriers to implementing surgical smoke evacuation in order to guide future improvement strategies. Methods: Based on previous studies, the main barriers faced by surgical nurses when implementing smoke evacuation include insufficient awareness and knowledge, lack of institutional policies, limited availability or inappropriate configuration of local smoke evacuation systems, disruptive noise from equipment, and associated costs. Results: Future strategies to address these challenges should focus on enhancing nurses’awareness of surgical smoke hazards. The adoption of hybrid educational approaches is recommended to reinforce knowledge and support practical application in clinical settings. Conclusion: This study’s suggestions for clinical practice include formulating standard operating procedures, drafting a local operation checklist for smoke clearance, and incorporating surgical smoke courses into the required annual continuing education credits for operating room nurses.