When goods are delivered sequentially each day from the dispatch station to the receiving station, and customers have specific delivery time requirements, effective route planning becomes essential. Proper planning not only enables optimal delivery within the given time window constraints, but also maximizes cargo loading while designing the most efficient vehicle routes, thereby reducing transportation costs. This research focuses on solving the logistics routing problem under both time and weight constraints. The key challenges include: (1) maximizing cargo loading capacity and minimizing total travel distance within a fixed number of vehicles; (2) considering customer-specified delivery time windows in addition to vehicle capacity during route planning; (3) dealing with the NP-Hard nature of the problem, which involves high computational complexity; and (4) ensuring that all vehicles depart from and return to a central distribution station, forming a single closed-loop route with no sub-routes allowed. To address the cargo allocation problem, this study adopts the Next Fit algorithm. For route planning, the A* algorithm is selected after comparative analysis and is further integrated with Integer Linear Programming (ILP) to impose constraints and optimize the solution. Finally, the effectiveness of the proposed approach is validated using Solomon’s benchmark problems for vehicle routing with time windows.