In this paper, we propose a constant voltage voltammetry potentiostat for detecting caffeine utilizes a microprocessor chip based on the ARM Cortex-M3 design, specifically the Silicon Labs EFM32, as its control core. The instrument employs commercially available printed circuit electrode boards as caffeine sensors, with control facilitated through the EFM32’s Universal Asynchronous Receiver-Transmitter (UART), interfacing with a LabVIEW human-machine interface on a personal computer. For system verification, standard solutions of different caffeine concentrations are applied to the detection area of the printed circuit electrodes. Two common electrochemical measurement techniques are utilized: cyclic voltammetry and fixed voltage voltammetry. Through cyclic voltammetry analysis of the caffeine standard solutions, the oxidation peak potential of the sensor is obtained. This oxidation peak potential is then used to set the voltage for fixed voltage voltammetry, forming the basis for the electrochemical analysis method of detecting caffeine using the sensor. Experimental results are observed through the LabVIEW interface. Finally, a calibration curve for the developed caffeine sensor is established, and the results are compared with data obtained from a commercial potentiostat. In the future, the caffeine sensor designed in this system could be integrated into beverage cups for applications in detecting the caffeine concentration in commercially available beverages. This would enable users to quickly determine the caffeine content of their drinks, helping them avoid excessive caffeine intake throughout the day.