Platforms, business ecosystems, and platform ecosystems have rapidly developed into important business models through the connection and catalysis of digitalization. Therefore, the strategies of a platform are an essential issue in strategic management. Platform strategies leverage the price subsidy strategy to induce the network externality. However, price subsidy is a strategy that is easy to imitate and will erode the performance outcome of the platform. Can price subsidies bring network effects to the platform? This has led to the controversy of “chicken-and-eggs”. Our knowledge regarding the relationship between price subsidy and platform operating performance is still limited. Based on the debates of prior research, by using e-commerce platforms as the research object, this study aims to answer the following research question: what is the path and contingency that the price subsidy strategy influences the performance outcome of e-commerce platforms? Evidence from 72 e-commerce platforms shows that the intensity of using a price subsidy strategy can hurte-commerce platform performance. Multi-homing plays a mediating role in the relationship between price subsidy strategy and e-commerce platform performance. Strictness of platform service terms for unilateral markets can moderate the relationship among multi-homing, price subsidy strategy, and e-commerce platform performance.