Purpose: The purpose of this study was to investigate the gender differences in the association between body mass index (BMI) and depression status among middle-aged and elderly people living in the community in Taiwan.
Methods: This is a cross-sectional study in northern Taiwan. 243 males and 607 females, aged 50-80 years were eligible for analysis. The participants were categorized in different depression status base on questionnaire according to gender. We applied Center for Epidemiologic Studies Depression Scale 10-item version (CESD-10) questionnaire to evaluate participant’s depression status. The statistical methods of Chi-square test were used to explored the correlation between depression status and categorical variables, including education level, marital status, BMI, self-reported health status, current smoking, alcohol consumption, exercise, employment status, income, hypertension, diabetes, and hyperlipidemia. Furthermore, we also applied multivariate logistic regression analysis.
Results: A total of 850 participants, 243 men and 607 women, were included in the analysis. They were classified into 2 categories by CESD-10 score with cut-off point of 8 in male and female group respectively. There is a significant difference between BMI and depression status in women (p<0.01). However, no significant relationship (p=0.06) between BMI and depression status was found in male group. Multivariate logistic regression analysis indicated that BMI<18.5 subclass has a significant relationship (p=0.02, OR 3.76, 95% CI 1.23-11.46) with depression status in female group.
Conclusions: Our study suggests that BMI below 18.5 is an independent risk factor for depression in females. Thus, when we visit thin middle-aged and elderly female patient, performing depression screening method should be taken into account in our clinical practice, especially those BMI below 18.5.