台灣族群常見室內污染物的暴露與代謝症候群之相關性

The Duration of Common Indoor Pollutant Exposure Is Associated with Metabolic Syndrome in Taiwanese Population

目的：近來研究指出，室外環境汙染與代謝症候群具正相關性。然而，對於室內汙染與代謝症候群的相關探討仍較少。故本研究旨在探討常見室內汙染物（燒香、蚊香、香精）與代謝症候群之相關性。

方法：本橫斷研究之樣本來自臺灣人體生物資料庫，由2008-2014年，年齡介於30至75歲共5,000位民眾組成。透過問卷的方式收集基本人口學資料及暴露室內汙染物的時間，理學檢查量測身高、體重、腰圍、血壓及抽血檢驗空腹血糖、高密度膽固醇及三酸甘油酯。將暴露族群分為短暴露組（暴露時間未達每週6小時）及長暴露組（暴露時間為每週6小時以上）。以Stata v.16.0進行多變項邏輯迴歸檢定。

結果：在本研究中，共1,004受試者屬於暴露組，其中733位為短暴露組，271位為長暴露組。與未暴露組相比，暴露組較年輕，較高比例為女性、吸菸者、二手菸的暴露，有較差的飲食習慣且沒有規律運動的習慣；共1,043位受試者具代謝症候群（盛行率：20.86%），在控制相關變項後，長暴露組與未暴露組相比，有較高代謝症候群的風險(aOR 1.47, 95% CI 1.06-2.04)。進一步分析代謝症候群的五項指標，在控制相關變項後，長暴露組與未暴露組相比，有較高的高三酸甘油酯風險(aOR 1.37, 95% CI 1.03-1.82)，而短暴露組與未暴露組相比，在代謝症候群及高三酸甘油酯的風險，均未達到統計上顯著差異。

結論：本研究顯示暴露於常見室內汙染物每週達6小時以上，與代謝症候群呈現正相關性。

 

Purpose: This study aimed to investigate the association between the exposure time to indoor air pollutants and metabolic syndrome (MetS) in the Taiwanese population.

Methods: A cross-sectional survey was conducted in a sample of 5,000 participants recruited from the Taiwan Biobank between December 2008 and May 2014. The exposed group’s characteristics were the following: regularly burned incense, burned at-home mosquito-repellent coil, or were exposed to essence for at least 5 minutes. This group was further divided into two categories: shorter exposure duration (exposure time <6 hours per week) group and longer exposure duration (exposure time ≥6 hours per week) group. Multiple logistic regression was used to investigate the relationship between the duration of indoor air pollutants exposure and MetS.

Results: In multiple logistic regression analysis, on comparison to the nonexposed group after adjusting the confounding variables, we found that the prevalence of MetS was higher in the longer exposure time group (adjusted odd ratio [aOR] 1.47, 95% CI 1.06-2.04, p=0.019). Regarding the components of MetS, we observed a positive association between the longer exposure time group and hypertriglyceridemia (aOR 1.37, 95% CI 1.03-1.82, p=0.032).

Conclusion: In summary, those exposed to indoor air pollutants, including regular incense burning, at-home mosquito-repellent coil burning, and/or essence use for ≥6 hours per week had an increased risk of MetS in the studied population.