The Overhead Conveyor (OHCV) and Stocker (STK) are most frequently used transportation and storage systems in high-tech factories and should not stop operation in an earthquake. However, these two systems are vulnerable to earthquake based on the Taiwan experience. In 2016 during Meinong Earthquake, damage of these two systems led to serious impact on high-tech factories. It not only shut down the production line, caused huge economical lose, but also delayed recovery process. This study aims to increase the seismic capacity of OHCV and STK for a high-tech factory. First, a rough numerical model to realize the true response under earthquake in the clean room was developed. By using full-scale static test and shaking table test, we can validate the dynamic characteristic of the numerical models. By considering the in-site situation, construction feasibility, and the economic demand, retrofitted bracing systems are developed. The strength of bracing is verified by component tests. Then, the efficiency for retrofitted OHCV and STK is verified by static tests and shaking table tests. Finally, the computed response in fab showed a drastically reduced response after the proposed retrofit.