髓鞘寡突膠質細胞糖蛋白抗體相關疾病

髓鞘寡突膠質細胞糖蛋白抗體相關疾病，是一種危急且致命的疾病，臨床進展快速、不具特異性、不易診斷，若無法及時正確診斷及治療，對於日後生活更是造成影響。本篇探討1位48歲女性，因反覆肢體無力、肢體麻木及失語症表現，經過詳細病史詢問、身體評估、安排相關實驗室檢驗、影像檢查，包括接受多次磁振造影檢查，整體性評估後疑似為炎症性或脫髓鞘病變，接受靜脈注射脈衝式高劑量類固醇治療，最後診斷為髓鞘寡突膠質細胞糖蛋白抗體相關疾病之病例報告。藉此案例分享，讓臨床醫護人員了解此疾病進程及相關照護，減少殘疾與失能發生。建議未來專科增加此疾病的教育指導與照護分享，提升醫療照護品質，提升生活品質。

The disease associated with antibodies against myelin oligodendrocyte glycoprotein (MOG) is a critical and potentially fatal condition. It progresses rapidly, lacks specificity in clinical presentation, and is challenging to diagnose. Without timely and accurate diagnosis and treatment, it can significantly impact the patient's future life. This case study explores a 48-year-old female presenting with recurrent limb weakness, limb numbness, and expressive aphasia. A comprehensive assessment was conducted using detailed medical history, physical examination, relevant laboratory tests, and imaging studies, including multiple magnetic resonance imaging scans. The patient was suspected to have an inflammatory or demyelinating disorder, received intravenous pulse high-dose corticosteroid therapy, and was ultimately diagnosed with a case of disease related to antibodies against myelin oligodendrocyte glycoprotein. This case report aims to share insights for clinical healthcare professionals to understand the progression and care associated with this disease, ultimately reducing the occurrence of disability and impairment. It is recommended that future medical education and care-sharing initiatives in specialized fields should focus on enhancing awareness of this disease, thereby improving the quality of healthcare and overall quality of life.