Development of an idiotypic vaccine against Vibrio harveyi in grouper

Development of an idiotypic vaccine against Vibrio harveyi in grouper

Aquaculture in Taiwan has become an important industry. Grouper, a fanned fish species with high economic value, has rapidly developed and become an important flagship product of Taiwan's top five high-quality agriculture. However, the grouper aquaculture is concentrated in the southern Taiwan and the intensification of fish culture has also been accompanied by the outbreaks of many infectious diseases, causing dramatic reduction in grouper production. The grouper aquaculture has suffered several pathogens. Among them, Vibrio bacteria leading to vibriosis are major bacterial pathogens causing a massive death of group and resulting in a significant economic loss. According to the previous data in 2003 year, Gram-negative bacteria isolated from the grouper fauns was 75%, in which the detection rate of Vibrio was up to 88%.