Establish the virus like particle vaccine technology and rapid diagnostic kit platforms

Establish the virus like particle vaccine technology and rapid diagnostic kit platforms

Disease rapid diagnostic kit and vaccines are very Important for animals healthy. In our research, we establish the rapid diagnostic kit and virus like particle vaccine platforms for animal health Vaccination is considered the most cost-effective way to control pathogens and prevent diseases both m human and veterinary field. Currently, the majority of licensed vaccines are either live attenuated or killed, developed using conventional technologies. However, new subunit vaccines are getting a foothold in the veterinary vaccinology, and among these, virus-like particles (VLPs) represent one of the most appealing approaches. VLP vaccines combine many of the advantages of whole-virus vaccines and recombinant subunit vaccines, integrating key features that underlay their immunogenicity, safety and protective potential: (1) preservation of native antigenic conformation, (2) safety, as they are absolutely non-infectious and nonreplicating candidates, (3) higher stability than soluble antigens in extreme environmental conditions, (4) self-adjuvanting immunogenic delivery systems. Moreover, we establish the VLP vaccine platform for chicken Infectious bursal disease (IBD) vaccine development.