"The case study mainly explored the development of the '2+2+2 mode' teaching program of our country’s innovative teacher training system, and explored the use of off-campus resources such as natural science museums by university professors, museum-style immersive learning, and collaborative teaching by industry teachers. The implementation of social action, the development of e-books for the development of multicultural education and teaching for students of the special education program, and other integrated teaching strategies that promoted the development of the 'multicultural education and teaching knowledge' of Teacher Professional Master Degree Program students. Therefore, the purposes of this research were four: 1. To explore the innovative teacher training system '2+2+2 mode' teaching and learning program development; 2. To analyze the related research of 'multicultural education teaching knowledge', information technology and multicultural education and learning. 3. To analyze the current situation, differences and correlations between 'e-book teaching' and 'multicultural education teaching knowledge' of students of Teacher Professional Master Degree Program. 4. Based on the above results, it proposed the theories and practical recommendations that teacher training education used electronic book teaching to develop multicultural education teaching knowledge."