市售茵陳蒿類藥材之鑑別   全文下載

Studies on the Identification of Artemisiae Scopariae Herbal Medicine in Taiwan

依臺灣中藥典規範茵陳藥材（Artemisiae Scopariae Herba）基原為植物濱蒿Artemisia scoparia Waldst. et Kit.或茵陳蒿A. capillaris Thunb.之乾燥地上部。春季採收之幼苗習稱「綿茵陳」，秋季採割帶花蕾則習稱「茵陳蒿」。許多文獻中記載茵陳蒿有誤用及混用之情形，有鑑於此，本研究為瞭解台灣對於茵陳蒿類藥材之使用情形，蒐集市售茵陳蒿類藥材包括茵陳蒿（AcF）、綿茵陳（AcS）、青蒿（Aa）及北茵陳（Ov）等4品項藥材共36件，由生藥外觀、組織鏡檢及薄層層析鑑定其基原。研究結果發現4種藥材具有不同的生藥特徵可供鑑別，能有效地鑑定茵陳類藥材，以此方法鑑定市售茵陳蒿檢體，結果顯示誤用率為62.5％。本研究成果可運用於行政機關之業務執行及藥廠品管或中藥材業者用藥之參考，以保障民眾用藥安全。

In Taiwan Herbal Pharmacopeia, the botanical origin of Artemisiae Scopariae Herba is the dried aerial part of Artemisia scoparia Waldst. et Kit. or A. capillaris Thunb. The drug collected in spring is commonly called ''Mian Yin Chen'', and that collected in autumn with flower buds is commonly called ''Yin Chen Hau''. According to many literatures, there are a number of alternatives and adulterants. Therefore, this study investigated the commercial products of four kinds of wormwood including Yin Chen Hao (AcF), Mian Yin Chen (AcS), Cing Hao (Aa) and Bei Yin Chen (Ov), and a total of 36 herbal samples. Morphology, microscopy and thin layer chromatographic analysis were used to authenticate the botanical origins. The results show each kind has unique characters which can be applied to the identification of raw materials. The misuse rate on commercial Yin Chen Hao was 62.5% using these methods. This research can be utilized as a reference for identification and quality control for the public health departments, pharmaceutical companies and retail stores to ensure drug safety.