This article explores a 73-year-old nun, who was diagnosed with uremia due to hypertension, chronic renal failure, and organ aging. The patient chose peritoneal dialysis treatment after learning the various renal replacement therapies. During the period of care from December 8, 2017 to January 20, 2018, the author used a comprehensive geriatric assessment (CGA) as a research tool. Data was collected through observation, listening, interviews, and physical assessment to assess the case, and found that the case had three major health problems: anxiety, lack of knowledge, and less nutrients than the body needs. In the process of care, anxiety was reduced by listening, companionship, care and support. Relevant knowledge, nursing guidance and home visits were provided to increase her confidence and, nutritional needs were supplemented by cross-departmental diagnosis, counseling and health education. Under the holistic and continuous care mode, the case will learn to perform peritoneal dialysis treatment independently within a short period of time, thereby improving the quality of life and becoming a senior volunteer.