This case study involved a 30-year-old woman who was admitted to theintensive care unit due to sepsis-induced organ failure, which developed from a urinary tract infection. During the nursing period from January 14 to January 19, 2017, data were collected through observation, interviews, listening, electronic medical record review, and physical assessment. Assessment was performed using Gordon’s 11 functional health patterns, and a care plan was formulated in response to the patient’s health problems: altered renal tissue perfusion, existing infection, and anxiety. Body fluid electrolytes were replenished based on clinical and physical conditions to correct their balances. A collaborative care plan involving interdisciplinary teamwork was implemented in response to the sepsis-induced acute kidney injury to avoid the deterioration of the patient’s systematic functions, thereby reducing the blood creatinine value from 7.8 mg/dL to 4.3 mg/dL while maintaining the urine output index at ≥ 0.5 mL/kg/hr. The patient’s knowledge concerning urinary tract infection was enhanced to control the existing infection, with the patient’s white blood cell count and C-reactive protein dropping from 10.8*10 3 /μL to 7.6*10 3 /μL and 13.5 mg/dL to 7.6 mg/dL, respectively. Additionally, listening and communication skills, as well as provision of relevant care knowledge were used to alleviate the patient’s disease-induced anxiety and guide her in expressing her anxieties, thereby reducing the patient’s anxiety index from 18 to 10. This experience is shared while nurses are caring for patients with sepsis-induced acute kidneyinjury conditions.