The fire safety regulations of Taiwan require 10 m above high ceiling space to install discharge type sprinklers. Smoke exhaust is also required for high ceiling space. It has been known that the interaction of smoke flow and sprinkler droplets may cause smoke layer be inducedand draged down.A discharge sprinkler experiment was setup to test the phenomena of smoke and sprinkler droplets interaction. The test results show that either the sprinkler is of ceiling or wall types, the sprinkler action would induce the downward flow of smoke and may affect the safe egress from fire. The physical phenomena in the experimental results agree with FDS simulation results. The computer simulation results show that smaller high ceiling spaces would have greater interaction of smoke and sprinkler action. The computer simulation also shows that for smaller high ceiling spaces, ceiling type sprinklers action would cause faster downward induced smoke flow. More case of computer model was built to simulate the 3D computer simulation of fire smoke with FDS. The simulation results of the smoke disturbance were compared for the automatic sprinkling operation, and the results of the performance-based safety design method were compared and analyzed. To identify important factors that mitigate the smoke layers, and propose improvements to improve performance-based fire safety design.