Ever since the “Teacher Education Law” was implemented by Ministry of Education in 1994, teacher quality control has encountered challenges, because the teacher-training system changed from a one-track model to a multiple-track model. The decrease in the national birth rate is also affecting job opportunities in the education workplace, making teacher education today face even greater challenges. In recent years, global attention to spirituality has gradually increased, and the career consultation of spiritual orientation has become an emerging issue. Many studies have pointed out that individuals who are spiritually-oriented usually have greater confidence in career choices. Since teaching is a spiritually-oriented job, spiritual studies of pre-service teachers are very relevant to their career choices. This study investigates what the prime motivation of being a teacher is, and in view of it, whether it is from a pragmatic need or from career calling. The study also discusses how we get more inspiration from related research. Literature analysis explores the relationship between spirituality and career development of pre-service teachers. In addition, the study reviews the spiritually-oriented career calling scales in order to understand the development trend. The main results are twofold. One of the results shows that pre-service teachers possess more helping and altruistic traits than general college students. The other one result is that there are too few literature reviews referring to spiritually-oriented career development. The recommendation is that the Ministry of Education and universities should pay more attention on the internal traits of pre-service teachers and strengthen spiritually-oriented career guidance and counseling. Finally, this study provides pre-service teachers with a way to qualitatively examine their career calling.