The project aims to improve hemoglobin in peritoneal dialysis patients to improve anemia in patients. In our PD center, the ratio of hemoglobin values greater than 8.5 g/dL for 6 months was less than 90% in 2015, which was lower than the hospital evaluation criteria. We analyzed that the main reasons of low hemoglobin level include: malnutrition, low consumption of high-iron content foods due to lack of knowledge, poor compliance on erythropoietin injections, iron deficiency, and blood loss etc. Cross-team cooperation, document verification, education on high-iron and high-protein diets, education on anemia care, formulation of iron supplement procedures and provide reminders and dosage adjustment for erythropoietin to improve compliance for injections were used for improvement. After improvement through the project, the rate of patients who were tracked continuously for five months with hemoglobin greater than 8.5 g/dL was over 90%. The experience and improvement program from this project can be used as an important reference for peritoneal dialysis nurses to effectively improve hemoglobin in patients.