頭頸癌病人接受化學放射治療期間疲憊症狀及其對睡眠品質影響之探討

Evaluation of exercise and massage intervention for head and neck cancer patients after chemoradiation therapy

頭頸癌病人在經歷整個疾病和治療時，常會有疲憊、疼痛、失眠及情緒困擾的症狀，而睡眠障礙常會導致病人的疲憊、憂鬱及免疫功能下降。本研究的目的，主要是要探討頭頸癌病人接受化學放射治療期間疲憊症狀及其對睡眠品質影響。本研究採立意取樣方式決定參與之受試者，研究對象為頭頸癌病人。樣本來源為中部某醫學中心血液腫瘤科病房為主。研究工具包括自擬之「基本資料問卷」、「台灣版一般疲憊量表」及「維辛氏睡眠量表」進行資料收集。本研究共有52位頭頸癌患者參與，以男性居多佔92.3％、平均年齡為54歲。結果發現，疲憊與睡眠品質呈負相關，病人疲憊分數越高睡眠品質越差（r＝-0.512|p＜0.001）。血色素僅與病人的睡眠品質呈正相關達統計顯著意義（r＝0.278|p＝0.046），病人的血色素越高，病人的睡眠品質越好。病人的血色素值與其疲憊狀態呈負相關但未達統計顯著意義。控制干擾變項，如：年齡、治療種類及血色素後，疲憊程度與睡眠品質呈負相關。

Head and neck cancer patients often suffer from insomnia, pain, fatigue and mood disturbance during treatment period. Sleep disturbance causes fatigue, depression and low immune system function. Hence, this study aims to explore the relationship between fatigue and the quality of sleep in head and neck cancer patients received concurrent chemoradiotherapy. A quasi-experimental method was used in this study. The data were collected using subjective questionnaires including a personal information questionnaire, Verramn & Snyder-Halpen scale (VSH) and Taiwan general fatigue scale (TGFS). A total of 52 participants with diagnosed head and neck cancer were enrolled. Results of the study showed that a statistically significant negative relationship between fatigue and the quality of sleep (r = -0.512| p ＜ 0.001) was found. The level of hemoglobin was positively correlated with the quality of sleep and has a statistically significant (r = 0.278| p = 0.046). Patients who had higher hemoglobin levels tend to have better quality of sleep. There was a negative relationship was found between fatigue and the levels of hemoglobin, however, no statistically significant difference between them.