關節液之晶體

Synovial Fluid Crystals

從1983年6月至1984年10月，共有100例關節炎之病患曾在本院門診及住院當中接受過關節液之抽取及檢查。所有關節液皆例行性地以普通光學顯微鏡、及偏極光顯微鏡，檢視其內是否有某種晶體存在。部份關節液尚以電子顯微鏡檢視晶體。另外，本實驗室使用特殊染色法來作含鈣晶體之初步驗定。在此研究中，共發現37例關節炎之滑膜液內有MSU晶體，3例有CPPD晶體，1例有Apatite晶體。然在類風濕關節炎、退化性關節炎及其它血清陰性脊椎關節病變之關節液內，卻無一例出現有CPPD或Apatite晶體。臨床及實驗皆顯示痛風關節炎在中國人發生率相當高，而CPPD及Apatite晶體所引發之關節病變，卻較歐美之病患少見。

From June, 1983 to October, 1984, 100 consecutive patients with arthritis were received needle aspiration of joint fluids. All synovial fluids (SF) were examined with light microscope and polarized microscope for the crystal, particularly the monosodium urate (MSU) and calcium pyrophosphate dihydrate (CPPD) crystal. The alizarin red S stain was used as a screen test to detect calciumcontained crystals in SF. Looking for the tiny CPPD or apatite crystals, electron microscopic (EM) study of SF was done in some cases. In our study, MSU crystals was found in 37 SF, CPPD in 3, and apatite in 1. No CPPD or apatite crystal appeared in SF of other joint diseases, for instance, rheumatoid arthritis or osteoarthritis. Our result disclosed that the gouty arthritis seems quite common in Chinese, whereas CPPD or apatite- related arthropathy seems uncommon when compare to the western reports.