Liquid chromatographlc determination of amoxicillin preparatlons-Interlaboratory validation

A previously published column liquid chromatographic method proposed for the analysis of amoxicillin preparations was subjected to an interlaboratory validation. The method is rigorously defined in terms of performance requirements, yet allows a degree of flexibility to the individual analyst. Nine participating laboratories submitted results for the analysis of four samples in duplicate. Estimates for the repeatability and reproducibility of the method, expressed as relative standard deviations of the results of the analysis of amoxicillin preparations, were found to be less than 0.96% and 6.29%, respectively.