英文摘要 |
Understanding the impact of drugs, alcohol and medicine effect on the person under the influence is an important aspect of the traffic accident investigation. Attribution of responsibilities such as human factors, environmental factors and machinery factors in order to conclude the cause of the accidents and safety improvement measures are the purposes of each traffic accident investigation. In addition to alcohol-related traffic accident (approaching 10%), psychoactive substance (PS) impaired drivers (around 5%) are also on the rise making drug control an important modern-day concern. Establishing the threshold of each PS is of immediate interest for judiciary purpose in Taiwan (Criminal Code Article 185-3). Alcohol is removed from the body by a combination of mechanisms including xenobiotic metabolism and saturated metabolite secretion. Breath alcohol content (BrAC) and blood alcohol content (BAC) are the standard legal examination process used in forensic toxicology. Besides alcohol-impaired driving, the misuse illicit drugs of schedule I and II controlled drugs - including amphetamine, morphine, MDMA, cannabis, and cocaine; and sedative-hypnotic drugs such as diazepam have been increasing throughout the years. How the alcohol and PS affect the safety of driving has become an important topic for forensic examination and judicial adjudication. Using a variety of data from international allies to analyze and accredit the impaired driver under the uses of the PS become the important issue to affirm the traffic safety and regulation (Taiwan's Criminal Code Article 185-3, not safety driving crime). Poly-drug use by driver and the road safety risk with driving after consuming drugs and alcohol is extremely high. A lower limit should be set for certain drugs where they are found in combination with alcohol. These lower drug limits of many illicit and over-the-counter drugs are recommended when BAC above 20 or 50 mg/dL is detected. For future adjudication, it is critical to explore the cause of the accident and to clarify the incident to exclude DUI of psychoactive substances' pharmacodynamics and pharmacokinetics, that is needed to facilitate the accurate interpretation of the driver's mental state. |