市售化粧品中甲基異噻唑啉酮及甲基氯異噻唑啉酮等成分之品質監測

Survey on the contents of Methylisothiazolinone and Methylchloroisothiazolinone in Cosmetics Products Marketed in Taiwan

為瞭解市售化粧品中甲基異噻唑啉酮（Methylisothiazolinone, MI）及甲基氯異噻唑啉酮（Methylchloroisothiazolinone, MCI）等成分的含量，食藥署於104年2至4月間委由各縣市衛生局於百貨行、公司行號、藥粧店、便利商店、美容美髮材料行及美容中心等處抽驗檢體71件（國產品35件，輸入品36件），以高效能液相層析儀檢驗。結果顯示：1件國產品檢出MI 0.02%，超出規定使用限量0.01%。在外盒包裝或容器標示檢查方面，不符規定者9件，其中1件未標示製造廠名稱及廠址（國產），8件未標示注意事項（國產7件，輸入1件）。另查獲1件為未領有化粧品工廠登記證擅自製造，不符規定者均已函送地方衛生機關予以行政處理，本調查結果將提供行政管理參考。

This monitoring program aimed to quantify the contents of Methylisothiazolinone and Methylchloroisothiazolinone in cosmetic products marketed in Taiwan. There were 71 samples supported by local health bureaus of Taiwan which randomly collected from cosmetics stores, drug stores and pharmacies between February and April, 2015. These samples were analyzed for the contents of Methylisothiazolinone and Methylchloroisothiazolinone by high-performance liquid chromatography (HPLC). The results showed that 1 sample contained Methylisothiazolinone failed to comply with the allowed level which was 0.01% set by TFDA/MOHW. In addition, 9 samples (12.6%) violated the labeling regulation requirements.