| 中文摘要 |
天然藥物在世界各國幾千年來，曾被用來作為傳統醫學之主要治療藥物；而中藥的使用在台灣、中國及華人社會相當普遍，然而我們對中藥之療效很少以現代醫學研究之方法給予有系統的評估其藥效；尤其對中藥之藥理作用機轉，有效成分之分析等更應有深入之探討。基於學術研究本土化之理念，十多年前（1987 年）我們在台大醫學院藥理學研究所曾組成小規模之中草藥藥效評估研究群，並與國內十多位生藥、化學家合作，進行有關「活血化瘀」中草藥成分之生物活性分析。所謂「活血化瘀」，若以現代醫學之闡釋，應為：改善血液循環（improving circulation）、去除或防止血栓（antithrombotic）之意。Herbal plants have been used as important remedies in traditional medicines in many countries for hundreds of years. In oriental countries, some medicinal plants, so-called 'vasoactive-thrombolytic' drugs have been claimed for the treatment of patients to improve circulation, induce fibrinolysis or prevent thrombosis. In order to modernize and develop scientifically Chinese herbal medicine, we have cooperated with chemists in large-scale pharmacological screening of many components isolated from Chinese herbs or medicinal plants using bioassay-based step-by-step purifications. |
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