| 英文摘要 |
A pregnancy involving an abnormal mass alongside a coexisting normal fetus is a rare and complex clinical scenario. The presence of the abnormal mass can complicate the pregnancy, affect the growth and development of the normal fetus and can create complications for the mother. This study reports the case of a 33-year-old patient who presented with concerns regarding an abnormal mass that was detected during an early pregnancy examination. The patient had abnormalities in the embryo sac and an unusually high human chorionic gonadotropin (β-hCG) level of 40,218 mIU/mL at approximately 6 weeks’gestation.
Continuous monitoring showed that theβ-hCG level had increased abnormally to 222,262 mIU/mL by the eighth week of pregnancy, and the patient continued to suffer from severe nausea and vomiting. These elevated levels persisted until the termination of the pregnancy, at which point they decreased. Chromosomal analysis of villous stromal cells revealed a normal fetal karyotype (46,XX). Immunohistochemistry showed positive p57 staining in villous stromal cells and cytotrophoblasts, and the Ki‑67 labeling index remained unchanged. Due to the risk of developing gestational trophoblastic neoplasia (GTN), regular clinical evaluations andβ-hCG monitoring were undertaken. Ultrasound examinations were to continuously track fetal development to ensure a normal pregnancy and to eliminate molar pregnancy. |
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