台灣卵巢癌的流行病學與預後：2001~2018

Epidemiology and prognosis of ovarian cancer in Taiwan: 2001-2018

這項研究探討了台灣卵巢癌的流行病學特徵，並分析了台灣自2001年至2018年間的卵巢癌發生率、死亡率及存活率的變化趨勢。根據Globocan 2020年數據，卵巢癌是女性常見的第八大癌症，其發生率在不同地區存在顯著差異。研究發現，台灣卵巢癌新發病例數逐年增加，發生率最高的區域為北台灣，年齡標準化發生率從2001年的6.42上升至2018年的8.9，每年增加約2%。此外，死亡率也呈上升趨勢，特別是在中台灣。研究顯示，上皮性卵巢癌、腫瘤大於5公分、較高期別及異常CA-125值為預後不良的主要因素。本研究的結果可為臨床醫生制定卵巢癌篩檢及治療策略提供參考，但由於個案數量和時間限制，部分重要的議題仍需進一步探討。

This study explores the epidemiological characteristics of ovarian cancer in Taiwan, analyzing the trends in incidence, mortality, and the trend of survival of ovarian cancer in Taiwan from 2001 to 2018. According to Globocan 2020 data, ovarian cancer is the eighth most common cancer among women, with significant variations in incidence across different regions. The study found that the number of new ovarian cancer cases in Taiwan has been increasing annually, with the highest incidence rate observed in Northern Taiwan. The age-standardized incidence rate increased from 6.42 in 2001 to 8.9 in 2018, with an annual increase of approximately 2%. Additionally, the mortality rate has also shown an upward trend, particularly in Central Taiwan. The study indicates that epithelial ovarian cancer, tumor size greater than 5 cm, advanced stage, and abnormal CA-125 levels are major factors associated with poor prognosis. The results of this study can provide a reference for clinicians in formulating screening and treatment strategies for ovarian cancer. However, due to limitations in the number of cases and time constraints, some important issues still require further investigation.