This article described the nursing experience for a terminal hepatoma patient from April 2 to May 2,2012. The patient was interviewed by therapeutic talks, physical assessment, observation, and nursing care. By using Gordon s functional health assessment, three major health problems were identified, including pain, hopelessness, and anticipatory grieving are found. Cancer pain was assessed during nursing process and controlled by medications, non-medication pain relief methods, such as essential oils massage and comfortable position. However, with the rapid deterioration of the disease, hopelessness and depression were found in the case. By the establishment of hope and life, spiritual sustenance, the patient experienced the value of life in the face of the fear of death. Through genuine care, listening, companionship, communication, confidence-building therapeutic relationships, we guided the family and the patient to walk out of the shadow of death. This nursing experience stresses the need for spiritual care for terminal cancer patients and their family.