Oral cancer is commonly associated with pain and fungating wounds. Thus, providing patients with approaches to mitigate this condition is necessary. This study investigated a patient with oral cancer and comorbid fungating wounds. The patient received nursing care between December 10, 2012 and January 12, 2013. This study implemented the Roy adaptation model as an evaluation framework, collecting and analysing data based on various methods (e.g., observations, written communication, interviews with family members, physical evaluations, and direct care) to determine problems of the patient, such as chronic pain, impaired tissue integrity, body image disturbances, and feelings of hopelessness. During the process of nursing care, we furnished a comfortable environment for the patient to alleviate their pain. In this environment, the patient was taught sudarshan kriya practices and progressive muscle relaxation methods, in order to divert his attention and relax him during dressing changes. In addition, we performed timely assessments of variation in the wound, taught the patient appropriate positioning to avoid applying pressure to tissues and hindering blood circulation. By listening to the patient’s concerns, we determined the patient’s feelings regarding changes in body image resulting from the wounds, willingness for self-care, and positivity toward wound conditions. Through experience sharing, this study expects to provide nurses with a nursing care reference.