In this paper, we take Determinative-Measure Compounds as an example to demonstrate how the E-HowNet semantic composition mechanism works in deriving the sense representations for all determinative-measure (DM) compounds which is an open set. We define the sense of a closed set of each individual determinative and measure word in E-HowNet representation exhaustively. We then make semantic composition rules to produce candidate sense representations for any newly coined DM. Then we review development set to design sense disambiguation rules. We use these heuristic disambiguation rules to determine the correct context-dependent sense of a DM and its E-HowNet representation. The experiment shows that the current model reaches 88% accuracy in DM identification and sense derivation.