花青素對第二型糖尿病功效之探討

The Function of Anthocyanins on Type 2 Diabetes

一些以細胞株系、模式動物以及人類臨床試驗的研究結果顯示：花青素對第二型糖尿病患者（T2D）有很好的功效。因花青素種類繁多，目前仍難明確指出那一種花青素在第二型糖尿病（T2D）的效果最好。然而，花青素主結構大致相同，且常見於食物中，符合目前葯食同源之主流看法。因此將成為健康食之選項。本文就花青素之結構式，及已有之試驗報告加以整理，探討其可能預防第二型糖尿病之可行性，以做為飲食之參考。

Numbers of reports according to studies with cell lines, animal models and clinical trials in humans showed that anthocyanins have anti-diabetic properties. However, there are so many anthocyanins with different structure existing in nature, make it difficult to determine their effects on type 2 diabetes. Published data suggest that anthocyanins may lower blood glucose by improving insulin resistance, protecting ß cell , increasing secretion of insulin and reducing digestion of sugars in the small intestine. As anthocyanins are abound in nature and the main structure of anthocyanins are the same can be supplement by diet, in line with the current mainstream of use food as a supplemental for health. In this paper, the structure of anthocyanins, and the existing reports to be collated to explore its possible prevention of the feasibility of type 2 diabetes, as a reference for the diet.