原發性修格蘭氏症候群合併腎絲球腎炎及肺部侵犯之一病例報告

Glomerulonephritis and Pulmonary Involvement in a Patient with Primary Sjögren's syndrome

原發性修格蘭氏症候群侵犯腎臟在臨床上並不多見。以膜增生性腎絲球腎炎為原發性修格蘭氏症候群的臨床表現更只有少數的病例報告。本文報告一25歲之男性患有眼乾及口乾數年之久，表現重度蛋白尿及血清IgA濃度偏高，而腎臟病理切片顯示出典型之膜增生性腎絲球腎炎以及間質性腎炎。

Primary Sjögren's syndrome with renal involvement is a rare manifestation. The presentation of membranoproliferative glomerulonephritis (MPGN) in primary Sjögren's syndrome was only reported in few cases. Here, we described a male patient who seized with dry eye and dry mouth for years, high serum IgA level and heavy proteinuria. Renal biopsy showed typical pictures of MPGN and interstitial nephritis.