血管張力素轉化酶基因與優秀跆拳道選手之關係

The relationship between angiotensin converting enzyme gene and elite Taekwondo athletes

"近年來運動科學的發展已進入了分子生物學領域。血管張力素轉化酶基因被認為與心血管耐力表現有關。目的：本研究探討優秀跆拳道選手與一般人其血管張力素轉化酶基因之多形性差異。方法：本實驗室徵召了40名優秀跆拳道運動員（男20、女20）中當實驗組，男女各101及82名一般人當對照組，血管張力素轉化酶基因之分型由聚合酶鏈鎖反應決定。In recent years, the development of sports science has entered into the molecular biology area. Angiotensin converting enzyme gene (ACE) is considered to be related to cardiovascular endurance performance. Purpose: The study investigated the difference of ACE gene polymorphism in elite taekwondo athletes and control group. Methods: 40 elite athletes (20males and 20females) were designed as an experiment team and another 183 ordinary people (101 males and 82 females, respectively) for control group. The genotype of ACE was determined by polymerase chain reaction (PCR) method. Results: Our result showed that II/ID/DD polymorphism frequency of male elite athlete are 45%/35%/20%, female are 50%/40%/10%; the control group male are 35.6%/47.5%/16.9%, female are 36.6%/46.3%/17.1%. There is an obvious difference (p<.05) in the elite athletes and control group. Conclusion: The ACE polymorphism is related to the performance of elite athletes. We may apply the test of ACE polymorphism in selecting the athletes and strategy application as a reference."