癲癇青少年生活品質量表（QOLIEA）之發展與信、效度檢定

Development and Validation of the Quality of Life Inventory for Epileptic Adolescents

本文旨在發展癲癇青少年生活品質量表QOLIEA並建立其信度與效度。QOLIEA乃經文獻查證、參考相關量表、焦點團體訪談資料、專家意見及項目分析等過程發展，包括：生理功能、心理功能、社會功能、認知功能與疾病／治療相關症狀等五次量表，共53題，適用於10～18歲之癲癇青少年。本研究收集92位10～18歲之癲癇青少年及其主要照顧者以建立QOLIEA的信度與效度，發現QOLIEA具有不錯的內在一致性、再測信度、內容效度、輻合效度、效標效度及臨床效度，但有三個次量表的結果無法證實其辨別效度是否良好。QOLIEA是國內目前唯一針對癲癇青少年設計的本土化生活品質量表，可由青少年本身自評其生活品質的問題與需求，進而提供醫護人員於臨床評價護理措施及醫療處置成效的參考，以促進癲癇青少年的生活品質。

The aims of this article were to develop a Quality of Life Inventory for Epileptic Adolescents (QOLIEA) and to demonstrate it’s reliability and validity. The item pool of QOLIEA was developed by literature review, relevant instrument (QOLIE-AD-48), qualitative study of an adolescents’ focus group interviews, and experts’ suggestions. There were 53 items including subscales of functions of physical, psychological, social, cognitive, and disease/treatment related symptoms. In order to demonstrate the reliability and validity of QOLIEA, 92 adolescents with epilepsy and their major caregiver were recruited. The results indicated that QOLIEA had good internal consistency reliability, test-retest reliability, content validity, convergent validity, criterion-related validity, and clinical validity. However, some results of discriminate validity did not support the hypothesis. This study demonstrated that the QOLIEA was a reliable and valid measurement for health-related quality of life for epileptic adolescents. It is a fair instrument to evaluate outcomes of nursing and medical interventions.