In the contemporary world, human beings are facing complicated or complex crises, but from a religious perspective, they can return to the spiritual crisis of human nature. In other words, the re-cultivation and even rebirth of human spiritual life can provide an opportunity to resolve or at least dissolve the crisis-complex of the contemporary world. In this paper, after briefly revealing the crisis of human spiritual life in the contemporary world and the spiritual origin and fall - the evolution of the world view and life view in the history of human culture, this article will start from the so-called systemic philosophizing, then firstly, we will reveal the basic meaning of systemic spirituality. This is followed by a systemic exploration of the integrative personality and corresponding life, and the spiritual cultivation and life practice of such personality in the context of the holistic system.