As COVID-19 was the first global pandemic of the digital age, many countries utilized information technologies and big data as technological epidemic prevention measures which led to controversies regarding personal data misuse, privacy invasion, and security risks. The mixed-method study used big data and content analysis to examine Taiwanese news reports related to personal data, privacy, and security issues in early COVID-19 outbreak. In contrast to Western studies, the results revealed that Taiwanese media reports, under infodemic influences, emphasized the importance of data security over that of protecting personal data and data privacy. Based on news framing of public health crisis, content analysis results showed the dominant use of action framing was followed by consequence and assurance framing, whereas negative framing (conflict and uncertainty) was rarely employed. The news reports about personal data, privacy, and security found statistical differences among three epidemic periods, as did their selection of news framing.