The purpose of this study was to investigate the effectiveness of the integration program for transition from discharge preparation to home-based medical care. A total of 341 referrals to home-based medical care services were recommended based on the integration program at a regional hospital in northern Taiwan from March 2018 to December 2021. Statistics showed that the rate of holding transdisciplinary meetings for discharge preparation during hospitalization was 75%. The rate of successful referrals was 83.9%, and the rate of readmission within 14 days was 1.2%. 35 (10.3%) of the patients agreeing to the referral also received long-term care assessment at the hospital, and 33 (9.7%) were recipients of advanced home-based medical care. With the transdisciplinary meetings coordinated by the discharge preparation service team to integrate and refer resources, the patient-centered integration program is capable of helping disabled patients receive needed long-term care assessment and home-based medical care services in the different stages of their illness after returning to the community.