Oxford-AstraZeneca COVID-19 疫苗引發的血栓及因應方式

Oxford-AstraZeneca COVID-19 Vaccine-induced Immune Thrombotic Thrombocytopenia: What We Need to Know

歐洲各國陸續出現在施打牛津阿斯特捷利康新冠肺炎疫苗後出現腦竇靜脈血栓和血小板過低症的案例，此現象已被命名為疫苗誘導的免疫性血栓性血小板過低症。目前發生疫苗誘導的免疫性血栓性血小板過低症的機轉仍未完全確立，且對於亞洲人的風險仍舊不明。本專論探討牛津阿斯特捷利康新冠肺炎疫苗相關之疫苗誘導的免疫性血栓性血小板過低症的流行病學、機轉、診斷標準及治療。

 

European countries have reported several cases of cerebral sinus vein thrombosis and thrombocytopenia in patients who received the Oxford-AstraZeneca COVID-19 vaccines. This phenomenon is now called vaccine-induced immune thrombotic thrombocytopenia (VITT). The mechanism of VITT and its risks for Asians are still unclear. In this monograph, the epidemiology, mechanism, diagnostic criteria, and treatments of VITT are briefly reviewed.