探討高頻胸壁振盪治療改善呼吸系統疾病病患之成效:系統性文獻回顧

Exploring the Efficacy of High-Frequency Chest Wall Oscillation Therapy in Improving Patients with Respiratory Diseases: A Systematic Review

呼吸系統疾病因支氣管分泌物增加且黏膜纖毛功能降低，進而導致肺部擴張不全或肺葉塌陷的風險，嚴重時則會引發呼吸衰竭之現象，許多研究顯示高頻胸壁振盪治療可用於呼吸系統疾病病患之輔助治療，但對病患之成效不一，故須進一步檢視其實質成效及有效證據。本研究以系統性文獻回顧探討高頻胸壁振盪治療改善呼吸系統疾病病患之成效，搜尋資料庫包含：華藝線上圖書館之CEPS及CETD中文資料庫、臺灣碩博士論文知識加值系統；CINAHL Plus with Full Text、Medline、PubMed、Cochrane Central Register of Controlled Trials、Google Scholar。本研究評定各篇文獻品質的評讀工具為Modified Jadad Scale量表。最後選定6篇文獻進行文章評讀與分析，Modified Jadad Scale分數多位於6.5至8分，屬於高品質研究。結果發現高頻胸壁振盪治療，有效性咳嗽和痰液咳出量優於控制組、胸部X-光肺部浸潤情形也有顯著性得到改善、血氧飽和度濃度上升、能有效改善肺功能、治療的耐受性良好且有更好的舒適度。高頻胸壁振盪治療，可有效清除痰液、改善胸部X-光肺部浸潤情形、提高血氧飽和度濃度、有效改善肺功能、且有更好的舒適度。建議未來研究可以探討高頻胸壁振盪治療多面向的成效，達到肺部疾病治療的目標。

The increased bronchial secretions and reduced mucociliary function in respiratory diseases lead to the risk of atelectasis or lung collapse, and in severe cases, respiratory failure. Many studies have shown that high-frequency chest wall oscillation therapy (HFCWO) can be used as an adjunctive therapy for patients with respiratory diseases, but effectiveness varies across patients. Therefore, the actual efficacy and valid evidence of the use of HFCWO need to be further reviewed. A systematic review was conducted in this study to explore the effectiveness of HFCWO therapy in improving patients with respiratory diseases. The searched databases included Chinese Electronic Periodicals Services (CEPS) and Chinese Electronic Theses and Dissertations (CETD) from the Chinese Databases of Airiti Library, National Digital Library of Theses and Dissertations in Taiwan, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus with Full Text, Medline, PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar. The Modified Jadad Scale was used in this study to evaluate the quality of each article. Finally, six articles were selected for article review and analysis, and their Modified Jadad Scale scores ranged mostly from 6.5 to 8, in what were considered to be high-quality studies. The results showed that HFCWO therapy was better than the control group in terms of effective cough and sputum output, that it showed significant improvement in pulmonary infiltration on chest X-ray, increased oxygen saturation concentration, effectively improved the lung functions, and had better tolerability and comfort. HFCWO therapy was found to clear sputum effectively, improve pulmonary infiltration on chest X-ray, increase oxygen saturation concentration, effectively improve lung functions, and enhance comfort. It is recommended that future studies investigate the effectiveness of HFCWO therapy from different aspects to achieve the goals of lung disease treatment.