反覆性風濕症發生率及盛行率：台灣全國人口2005年至2012年之世代研究

The Incidence and Prevalence of Palindromic Rheumatism in Taiwan During the Period 2005–2012: A Nationwide, Population-Based Study

目的：估算2005年至2012年間台灣反覆性風濕症的發生率與盛行率。方法：運用2003年至2012年健保資料庫，根據ICD-9-CM診斷碼719.3定義2005年至2012年新診斷之反覆性風濕症病患，估算其發生率及盛行率，並計算按年齡及性別分層之發生率與盛行率。結果：於2005年至2012年之間，反覆性風濕症在台灣之發生率介於每十萬人年3.01至4.29人，盛行率介於十萬分之16.21至41.95，死亡率則介於0.38%及0.59%之間。反覆性風濕症發生率在年齡0-9歲組是每十萬人年0.12人，隨年齡上升，在40-49歲組達到高峰，為每十萬人年6.40人；其發生率及盛行率在女性族群均高於男性，女男比例按年齡層不同，介於1.25到3.16倍之間。結論：本研究描述了反覆性風濕症於台灣的發生率及盛行率，發生率高峰在男女族群均隨年齡上升但男性族群其高峰發生較晚。此外，女性族群之發生率及盛行率均高於男性，且在年齡40-49歲組女男比達到3.16倍。

Objective: To calculate the incidence and prevalence of Palindromic Rheumatism (PR) in Taiwan during the period of 2005–2012.Methods: The study utilized 2003–2012 claims data from the Taiwanese National Health Insurance Research Database to identify all patients with a new diagnosis of PR (International Classification of Diseases, Ninth Revision code [ICD-9-CM] code 719.3). We estimated the age- and sex-specific incidence and prevalence of PR during 2005–2012.Results: For the period of 2005-2012, the incidence rate of PR in Taiwan ranged from 3.01 to 4.29 cases per 105 person-years, with the prevalence of PR ranging from 16.21 to 41.95 per 105. Mortality rate of patients with PR ranged from 0.38% to 0.59%. The age-specific incidence rate was lowest in the 0-9 age group and highest in the 40-49 age group, with 0.12 cases and 6.40 cases occurring per 105 person-years, respectively. Female predominance in both incidence and prevalence of PR was observed. The female to male ratio for incidence rate was 1.25 and 3.16, respectively, in the two different age groups. Conclusion: The present study outlines the incidence and prevalence rate of PR in Taiwan for the period covering 2005-2012. Peak incidence of PR increased with age in both genders, however male patients experienced a later peak than female patients. Furthermore, female predominance, with the highest female to male ratio of 3.16 being noticed, occurred in the 40-49 age group.