Mediatization, as a theory that depicts the “-interrelated changes-” between media and the overall social and cultural domains, is always restricted to the ontological dualism framework. Accordingly, separating mediatization from the shadow of determinism or “media effects” is challenging. This study introduces actor-network theory to reinterpret mediatization theory and also proposes a new “media-concerned” approach. This new approach regards mediatization as the interrelated changes in a controversy during the assembling process of all the human and non-human actors, especially media. The approach is media decentralized but media concerned to avoid determinism or reductionism. To illustrate how this new approach applies empirically, I use the controversy over the 2018 Taiwanese referendum for marriage equality is as an illustrative case. I also consider the advantages and disadvantages of this new approach and provides directions for further theoretical and methodological discussion.