A 52 year-old healthy woman visited our out-patient department for acute left low back pain. Urinary analysis led to an initial diagnosis of urinary tract infection, but antibiotic agent failed to alleviate her left low back pain. In the emergency department, left side pleural effusion was found accidentally by routine chest X-ray. Left lower lobe pneumonia with pleural effusion was confirmed by computed tomography later. Her left low back pain was improved after the treatment of levofloxacin. Acute low back pain may be an atypical extrapulmonary symptoms of pneumonia.