The purpose of this study was to investigate the students’ mathematical learning effectiveness of mathematical reading games on newspapers with instructions of cognitive and meta-cognitive strategies. The participants were three sixth grade classes of an elementary school in Tainan County, and a non-equivalent pre-posttest control group experiment was conducted. The instruments were quantitative data collected from students’ assessments and self-designed mathematical learning attitude and meta-cognition scale, and the qualitative data were collected from research discussion, classroom observation and interview. Data collected were analyzed by ANCOVA in SPSS to test correlated research hypothesis. The results showed as follows. First, there was no significant effect on sixth graders’ learning performances in mathematical reading games on newspaper. Secondly, males and females showed different learning styles, however, there was no relationship between learning styles, sex and mathematical learning effectiveness. Thirdly, Cognitive and meta-cognitive strategies instruction helped students clarify the question, comprehend problems, and express their ideas about mathematical tasks. However, students were poor at using the strategies of diagram and checking computation & problem-solving steps. Overall, the phenomenon of double-peak still existed, low achievers could not solve the problems successfully by using strategies. Finally, suggestions for classroom teachers and future studies were proposed.