Research topic is “Health Insurance Program for Children and Youths: Premium Subsidies Project of National Health Insurance for Disadvantaged Children and Youths” of Domestic Violence and Sexual Assault Prevention Center of Taoyuan City Government upon public welfare sponsorship for successively ten years. By interviewing important design personnel of the project and the practical workers who apply the said project, this study explores the origin, cooperation and change of “Taoyuan City Health Insurance Program for Children and Youths: Premium Subsidies Project of National Health Insurance for Disadvantaged Children and Youths” as reference for public and private sectors in the society. According to research findings, origin of “Taoyuan City Health Insurance Program for Children and Youths: Premium Subsidies Project of National Health Insurance for Disadvantaged Children and Youths” was based on the intention and profits of government and enterprise and the assistance of medium organization. Besides, at the time, there was the medical demand of disadvantaged children and youths. Thus, the project was established. The key factor in cooperation process was to meet the “expectation” of different sectors. Cooperation content also satisfied “individual requirement” of the collaborative units. Continuous cooperation factor was professional supervision of social workers in government.