大面積脂肪缺損於紅斑性狼瘡併狼瘡性脂膜炎

Extensive lipoatrophy on a buttock revealing lupus erythematosus panniculitis

A 41-year-old female presented with an area of tender swelling on her right buttock, which subsequently shrank forming an extensive depression after three months (Fig. 1a). Arthritis, malar rash, and oral ulcers were also noted. Serological studies showed positive ANA (1:160, nucleolar pattern) and positive anti-ds DNA (14.3 IU/mL; normal <10 IU/mL). She was diagnosed with systemic lupus erythematosus (SLE) since she fulfilled more than four criteria of the 1997 revised criteria for the classification of SLE. Her serum complement levels were within normal range (C3: 113 mg/dL; normal 90–180 mg/dL, C4: 29.6 mg/dL; normal 10–40 mg/dL).