類鼻疽在紅斑性狼瘡

Melioidosis in systemic lupus e1ythematosus

類鼻疽是會造成致死性的感染。在臨床上的表現是多樣性，從局部的感染至嚴重的菌血症。這疾病最常發生在免疫功能不全的病患，包括全身性紅斑狼瘡。我們發現在台灣第一個紅斑性狼瘡病例的個案。早期發現及給予適當的治療可顯著的降低死亡率。這篇文章是在報告一個容易致死的疾病，因為早期診斷並運用正確的抗生素而治療成功的個案。

Melioidosis is a potentially fatal infectious disease of humans. The clinical features of melioidosis vary, raging from localized, benign disease to fulminent septicaemia. The infection is more common in immunocompromised patients including systemic lupus erythematosus (SLE). We present a first case of melioidosis in lupus patient in Taiwan. Earlier investigation and appropriate antibiotic therapy are important to decrease the mortality. This case demonstrates how better outcome can be achieved in a frequently fatal disease if an early diagnosis is made and appropriate antibiotics are initiated promptly.