卵巢惡性混合的苗勒腫瘤：病例報告

Ovarian Malignant Mixed Mullerian Tumor: A Case Report

卵巢惡性混合苗勒腫瘤是極為罕見的婦科癌症。雖然有手術的進展以及鉑類藥物結合紫杉醇藥物作為術後藥物的治療，但相較於一般卵巢上皮癌而言，目前預後仍極差。我們報告一個67歲停經婦女經過上述的治療，目前仍存活的個案，來增加我們對這個病的瞭解。

Malignant mixed müllerian tumors (MMMT), are relatively rare gynecologic tumors that occur throughout the female genital tract, most commonly in the uterus. Ovarian MMMT is extremely rare with very poor prognosis. A 67-year-old menopausal woman had suffered from abdominal fullness. Evaluations showed massive ascites with suspicious heteroechoic pelvic mass by ultrasound, 1597 U/ml of serum CA-125 but negative for upper and lower gastrointestinal examination. Under the impression of ovarian malignancy, the patient underwent exploratory laparotomy with pelvic tumor and disseminated peritoneal carcinomatosis. Optimal debulking surgery was completed with surgical-pathological stage IIIC of ovarian MMMT, containing largely poorly differentiated carcinoma and focal chondrosarcoma. The patient is free of disease for one year. We concluded that optimal debulking surgery following the combination of paclitaxel and carboplatin is worthy of further evaluation, based on the relative success in this case.